Biotechnology Research and Education Program

Course Description

Lecture topics include

  • cell physiology and medium components
  • fermentors and accessories, probes and instrumentation
  • recombinant E. coli protein expression and fermentation
  • oxygen consumption and transfer data analysis
  • scale-up of fermentations: principles, practice and problems
  • case studies illustrating how principles are applied in practice

Laboratory sessions include

  • assembly and disassembly of bench top fermentors (2-5 liter) from several different vendors
  • sterilization procedures
  • preparation of inocula and inoculation
  • process sampling
  • measurement of optical density and glucose levels
  • process control
  • harvesting techniques

Workshop laboratory sessions

The workshop laboratory sessions take place in a newly renovated learning facility located within the University of Maryland Bioprocess Scale-up Facility (BSF) on the College Park campus. The BSF houses bioprocessing equipment for process development and optimization ranging from 1 L to 280 L. All workshop participants will examine and test large-scale fermentation equipment while they perform their own experiments on bench-top units provided by several vendors. The format is fast-paced, but plenty of time has been allocated for discussion with workshop faculty.

Case Studies

In response to requests from past attendees, a series of case studies are being added to the curriculum so that participants may gain a greater understanding of how the principles of fermentation are applied in practice. Please see the complete workshop schedule for more details.

Cost

  • Two-day Fermentation Microbiology workshop: $995
  • Fermentation and Downstream Workshops (5 days): $1,946.50 (15% discount for both workshops)
  • Lodging is not included in registration fee.

Meals

Continental breakfasts, catered lunches and coffee breaks will be provided, and are included in the registration fee.

 

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