Biotechnology Research and Education Program

Productivity Enhancement: Lean Bio Manufacturing Consulting

The most successful bio manufacturing companies utilize their resources efficiently. They bring products to market faster, meet production deadlines and minimize waste. The Biotechnology Research and Education Program's Productivity Enhancement consulting component applies "Lean Manufacturing," an operating philosophy focusing on eliminating mistakes and non-value adding activities, to bio manufacturing.

BREP consultants' areas of expertise include facility design and layout, process optimization and load balancing, material handling, logistics, and cellular manufacturing. They can also help companies be more productive in:

  • Workforce practices
  • Equipment selection/upgrades
  • Bioprocess monitoring and control
  • Process optimization
  • Cleaning and changeover time reduction
  • Maintenance practices
  • Mistake-proofing and standardization
  • Quality procedures and policies
  • Information flows

BREP staff utilize the following four-step approach for bio manufacturing consulting:

  • Step 1 — Opportunity Identification: We'll assess how your plant gets things done, work with you to identify a baseline, and identify high impact productivity enhancement opportunities.

  • Step 2 — Solution Design: An implementation plan is developed that details specific improvement opportunities and recommended implementation method and process.

  • Step 3 — Implementation: We'll assist in the implementation which may involve mentoring, facilitation, knowledge transfer, as well as joint implementation with your company's team. Pertinent training is provided to assure workforce understanding, buy-in, and commitment.

  • Step 4 — Continuous Improvement: Productivity Enhancement isn't something you do once and then forget about. It's an ongoing journey where the rewards get greater and greater. As you improve your productivity and get closer to meeting your business objectives, it's important to keep the momentum going. We can help you measure performance, hone your competitive edge and continually improve.

Companies planning a facility expansion or relocation can take advantage of the BREP staff's expert advice for contractor review, new equipment selection and floor layout design. Biotech team members can create computer simulations of the proposed facility to help companies evaluate alternative processing flows, while process development solutions can be tested in the BSF.

Perform higher, faster and more efficiently by employing BREP's Productivity Enhancement consulting services.


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